SynTech Synedrine fat burner 120 caps

SynTech's™ new fat burner is one of the most advanced on the market and completely formulated according to the most recent scientific findings in the field of fat burning. In the development of Synedrine, SynTech™ set three requirements:

1. It must work and be scientifically substantiated;
2. It must meet the strictest health and food safety requirements;
3. Synedrine should be easy to use.

Synedrine contains a blend of synergistically working ingredients that increase fat burning.

The key ingredients per daily serving

• A stack of 270mg EGCG (from green tea) and 300mg Caffeine (from guarana).
  As shown by various scientific studies, this combination already increases combustion by 180 kCal at rest. ²⁾
  That combinations of green tea and caffeine support fat burning, scientists at the University of Connecticut also concluded in a recent meta-study in which they pooled and analyzed data from 15 studies⁽³⁾:
• Phenols in green tea first and foremost inhibit the enzymes that break down adrenaline and noradrenaline. More adrenaline and noradrenaline means that the fat cells are more easily broken down into the blood, so that the muscles and organs can burn them. In addition, at the cell level, phenols have a similar effect. Phenols in green tea, such as EGCG, make the mitochondria in the cells burn more fatty acids. Caffeine makes cells more sensitive to adrenaline and green tea. A dose of 150mg of caffeine increases fat burning by 33 percent. If you add 270mg of EGCG, the most active polyphenol in green tea, the fat burning increases to 41 percent!
• Most manufacturers do put some green tea in their formulas (200mg on average), but this is far too little to get the amount of active EGCG. SynTech™ chose a mega dose of 1400mg green tea standardized to 19% to arrive at a daily dose of 270mg EGCG.
• 200mg Capsimax™ 
  Capsimax™ is a patented form ('patent pending') of Capsicum Annuum. In a clinical study from the University of Oklahoma, where Capsimax™ was administered 60 minutes before exercise, the supplement burned 278 more calories before, during and after exercise compared to a placebo. The study confirms findings from other studies that Capsicum Annuum improves thermogenesis and supports fat loss in men and women. Capsicum Annuum also improves fat oxidation and the consumption of fats needed for weight loss. ⁽⁶⁾
• 400mg Svetol®
  Svetol® is a natural extract of decaffeinated green coffee beans and has a significant effect on fat burning. It reduces body mass index (BMI) and increases lean muscle mass after 60 days. This is stated in a clinical study that the manufacturer has conducted in collaboration with the INRA (The French “Institut National de la Recherche Agronomique). ⁽⁷⁾ Svetol® consists of approximately 50% of chlorogenic acid. Chlorogenic acids are polyphenols with an anti-oxidative effect and which have been known for some time to be effective in slimming. According to the study, it is recommended to take 400 mg daily in one or more doses.
  According to another study published in Phytothérapie ⁽⁸⁾, subjects using Svetol® lost an average of 5 kg over a 60-day period. Other studies support those findings. ⁽⁹⁾⁽¹⁰⁾
• 210mg Taraxacum Officinale
  Taraxacum Officinale is a plant extract that contains natural water-repellent properties. It supports a more efficient removal of excess moisture from the membranes ⁽¹¹⁾ and thus helps to provide a “drier” look.
• 250mg Forslean®
  Forslean® is the patented extract of Coleus Forskohlii, standardized to 10% forskolin. Forslean® stimulates the breakdown of existing adipose tissue by increasing cAMP. CAMP is a molecule that plays an important role in various biological processes, including lipolysis. ²⁾ ⁽¹³⁾
• 10mg Bioperine®
  This patented form of black pepper extract ensures optimal absorption of the other ingredients.

Sources:

1. Safe weight loss stack: 300 milligrams of EGCG and 300 milligrams of caffeine per day (Source: jeancarper.com) October 14, 2006
2. Supplement with EGCG and caffeine increases combustion by 178 kcal (Source: J Nutr. 2005 Sep;94(3):432-6).
3. Meta-study: Green tea slimming supplements work (Source: Am J Clin Nutr. 2010 Jan; 91(1): 73-81).
4. Yoshioka M, et al: Effects of red-pepper diet on the energy metabolism in men. (Source: J Nutr Sci Vitaminol 1995; 41: 647–656).
5. Yoshioka M, et al: Effects of red pepper added to high-fat and high-carbohydrate meals on energy metabolism and substrate utilization in Japanese women. (Source: J Nutr 1998; 80:503–510).
6. Manuela PGM Lajeune et al: Effect of capsaicin on substrate oxidation and weight maintenance after modest body weight loss in human subjects. (Source: J Nutr 2003; 90:651-659).
7. INRA (Institut National de la Recherche Agronomique) (22/02/2007)
8. Dellalibera SO, Lemaire B & Lafay S. (2006) Le Svetol®, un extrait de café vert décaféiné, induit une perte de poids et augmente le ratio masse maigre sur masse grasse chez des volontaires en surcharge pondérale. Phytotherapy 4, 1-4.
9. Blum J, Lemaire B & Lafay S. (2007) Effect of a green decaffeinated coffee extract on glycemia – A pilot prospective clinical study. NUTRAfoods 6(3), 13-17.
10. Nardon K, Lemaire B & Lafay S. (2007) Green coffee extract Svetol® can manage weight: a review. AgroFOOD industry hi-tech 18(5 -Supplement), 37-39.
11. Racz-Kotilla, E., Racz, G., & Solomon, A. (1974). The action of Taraxacum officinale extracts on the body weight and diureses of laboratory animals. (Source: Planta Med; 26: 212-217).
12. Asano Tsuguyoshi (2001). Clinical report on root extract of perilla plant (Coleus forskohlii) ForsLean® in reducing body fat. Asano Institute, Tokyo, Japan.
13. Kreider RB, et al. Effects of Coleus forskohlii supplementation on body composition markers of health in sedentary overweight females. (Source: Experimental Biology 2002 Late Breaking Abstracts. LB305: 2002).